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About Childhood Asthma
Asthma is a chronic, long-term disease of the respiratory system that causes the bronchial tubes that carry air to the lungs to swell and become inflamed. When a child has asthma, these tubes may be swollen and clogged with mucus. At times, asthma can block or narrow the airways, making it difficult for your child to breathe. This is known as an asthma attack.1 Asthma attacks vary greatly — they can happen rarely or often, and they can be mild to severe. Although sometimes you may be able to deal with an attack at home, a severe attack may require a trip to the emergency room.
The symptoms of asthma in children include2:
  • Coughing, wheezing, shortness of breath, or rapid breathing
  • Tightness or pain in the chest
  • Excessive fatigue
What causes childhood asthma?
Doctors are still unsure exactly what causes asthma. They do know that many things cause the inflammation that can lead to asthma and asthma attacks. Some children are born with a tendency for asthma, and some children's immune systems overreact to triggers that cause inflammation and attacks. Common triggers include2,3:
  • Tobacco smoke
  • Stress
  • Pollen and mold
  • Dust mites
  • Cockroach particles
  • Air pollution
  • Animal dander (skin and saliva)
  • Cold weather
  • Exercise
For more information on avoiding asthma triggers, click here.
AccuNeb® (albuterol sulfate) Inhalation Solution is indicated for the relief of bronchospasm in patients 2 to 12 years of age with asthma (reversible obstructive airway disease).
Important Safety Information
In a clinical trial with AccuNeb® Inhalation Solution 0.63 mg, AccuNeb® Inhalation Solution 1.25 mg, and placebo, the most commonly reported adverse events were asthma exacerbations (11.1%, 13%, 8.5%), otitis media (0.9%, 4.3%, 0%), allergic reaction (3.4%, 0.9%, 1.7%), gastroenteritis (3.4%, 0.9%, 0.9%), and flu syndrome (2.6%, 2.6%, 1.7%).
Like other beta-adrenergic agonists, AccuNeb® Inhalation Solution can produce paradoxical bronchospasm, which may be life-threatening. AccuNeb® Inhalation Solution should be used with caution in patients with cardiovascular disorders and patients being treated with epinephrine, oral sympathomimetics, beta-blockers, MAOIs, or tricyclic antidepressants.
Please see Patient Prescribing Information.
References
1. Centers for Disease Control and Prevention. You can control your asthma. http://www.cdc.gov/asthma.faqs.htm. Accessed May 11, 2007.
2. National Heart Lung and Blood Institute. Diseases and conditions index: asthma. http://www.nhlbi.nih.gov/health/dci/Diseases/Asthma/Asthma_All.html. Accessed May 11, 2007.
3. American Academy of Allergy, Asthma & Immunology. Tips to remember: asthma triggers and management. http://www.aaaai.org/patients/publicedmat/tips/asthmatriggersandmgmt.stm. Accessed May 11, 2007.
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